专业研究领域为免疫学，主要研究方向为肠道与肺区域免疫，肺部相关疾病（哮喘、急性肺损伤
等）发病机理、诊断与治疗的探究。
2018
年入职于广州医科大学，并入选广州医科大学“南山学者后
备人才”培养计划，获得 100 万科研经费资助。主持国家自然科学基金青年项目一项，广东省基础与
应用基础研究项目一项，国家⾃然科学基⾦重⼤研究计划培育项目骨干成员。在 Journal of Experimental
Medicine, Plos Pathogen, Frontiers in Immunology
等国际高水平学术刊物上发表
SCI
论文
9
篇（第一作
者
/
通讯作者
4
篇）。担任国际知名期刊《
Military Medical Research; IF=34.9
》
,
《
Frontiers in immunology;
IF=8.7》,《Burns & Trauma; IF=5.7》科学编辑 (Scientific Editor); 并担任《Advanced Science; IF=17.5》,
《 Journal of translational medicine; IF=8.4》,《Burns & Trauma; IF=5.7》评审(Reviewer)。
2018.11-Present, Associate professor, Guangzhou medical university
1. Fang Hongwei#, Sun Zhun#, Chen Zhouyi#, Chen Anning, Sun Donglin, Kong Yan, Fang Hao*,
Qian Guojun*; Bioinformatics and Systems-Biology Analysis to Determine the Effects of Coronavirus
Disease 2019 on Patients with Allergic Asthma; Frontiers in immunology. 2022.08,
DOI:10.3389/fimmu.2022.988479.
2. Qian Guojun; Jiang Wei; Zou Benkun; Feng Jintao; Cheng Xiaofang; Gu Jie; Chu Tianqing; Niu
Chen; He Rui; Chu Yiwei; Lu Mingfang*; LPS inactivation by a host lipase allows lung epithelial cell
sensitization for allergic asthma, Journal of Experimental Medicine, 2018, 9(215): 2397-2412.
3. Qian Guojun; Chen Caiping; Zhou Rong; He Yanbin; Shao Weilan*; A thermostable
S-adenosylhomocysteine hydrolase from Thermotoga maritima: Properties and its application on S-adenosyl
homocysteine production with enzymatic cofactor regeneration, Enzyme and Microbial Technology, 2014,
64-65(64-65): 33-37.
4. Qian Guojun; Chen Caiping; Ruying Zhai; Shao Weilan; Yanzhen Mei*; Expression, puri fication
and characterization of a thermostable lactate dehydrogenase from Thermotoga maritima. Chinese Journal of
Biotechnology, 2014; 30:1–9.
代表性成果：
1.
国 家 自 然 科 学 基 金 青 年 项 目 ，
81901633
，
Bcl-3
调 控 过 敏 性 哮 喘 及 其 机 制 的 研 究 ，
2020/01-2022/12
，
22
万元，主持。
2. 广东省基础与应用基础研究，Jmjd3 调控过敏性哮喘及其机制的研究， 2023/04-2025/03，5 万
元，主持。
3.
国家自然科学基金重大研究计划培育项目，
91949102
，胸腺衰老和退化的表观遗传调控机制，
2020/01-2022/12
，
68
万，项目骨干。
Our group mainly investigates the pathogenies of inflammation-induced pulmonary disease, especially
allergic airway inflammation (asthma) and acute respiratory distress syndrome (bacterial lung injury,
COVID-19). We found that acyloxyacyl hydrolase promotes allergic inflammation by degrading gut-derived
LPS (JEM, 2018) and facilitates the resolution of LPS- or Gram-negative bacteria-induced lung injury (Plos
pathogen, 2017). Moreover, we identified several novel biomarkers of COVID-19 and asthma and
discovered several promising candidate drugs that might help treat patients with COVID-19 and asthma
(Frontiers in immunology, 2022).
姓名
钱国军
性别
男
电话
13262705810
邮箱
qianguojun@gzhmu.edu.cn
南山学者类别
全职引进
南山学者层次
后备人才
所在二级单位
附属肿瘤医院
学科分类
基础医学
科研领域
支气管哮喘、肺损伤、肠道菌群
2015.09-2018.06, Ph.D., Microbiology and Immunology, Fudan University, China.
2012.09-2015.07, M.S., Microbiology, Nanjing Normal University, China
2008.09-2012.07, B.S., Life sciences, Suzhou University, China
个人简介
工作经历
期刊论文
科研项目
团队介绍
教育经历
