照片 金召奎博士 广州医科大学 南山学者 骨干人才 2 016 毕业于北京科技大学材料物理与化学专 业,曾先后在深圳大学进行博士后和副研究员工作。近些年一直专注于纳米气体诊疗剂的可控释放、 靶向递送和重大疾病治疗机制的研究 主要研究方向 1 多功能纳米药物的设计合成 靶向气体传输 可控气体释放 外场 / 内环境响应性释放 对气体传输的医学成像引导和监控 基于气体治疗的多模 式联合治疗 2 纳米气体药物的机制和应用研究 甲烷气体生物学效应与机制研究 抗肿瘤耐药与抗 肿瘤转移;炎症相关性疾病应用研究(肺纤维化 / 糖脂代谢);气体增敏治疗; 3 )免疫调控:气体信 号分子介导的免疫调控和重大疾病治疗。已发表研究性论文 3 0 多篇,其中以第一 / 共同第一作者身份 Nature Communications Science Advances Advanced Materials National Science Review Nano Today Biomaterials 等国际著名期刊上发表了学术论文 1 8 篇,其中 IF 大于 10 9 篇,获得 6 项国家发明专 利授权。主持承担国家自然科学基金面上项目、青年项目、广东省自然科学基金面上项目、深圳市科 技计划项目基础研究等项目 5 项。 1. Tianfu Zhang*, You Pan, Meng Suo, Meng Lyu, Jacky Wing Yip Lam, Zhaokui Ji n *, Shipeng Ning*, Ben Zhong Tang*, Photothermal-Triggered Sulfur Oxide Gas Therapy Augments Type I Photodynamic Therapy for Potentiating Cancer Stem Cell Ablation and Inhibiting Radioresistant Tumor Recurrence, Advanced Science, 2023, 2304042. 2. Zhaokui Jin,# Yanhong Duo,# Yang Li , Meng Qiu, Mengna Jiang, Quan Liu, Penghe Zhao, Tian Yang, Xingkang He, Weiyuan Liang, Han Zhang*, Yihai Cao*, Qianjun He*, A novel NIR-responsive CO gas-releasing and hyperthermia-generating nanomedicine provides a curative approach for cancer therapy, Nano Today, 2021, 38, 101197. 3. Danyang Chen,# Zhaokui Jin,# Bin Zhao, Yingshuai Wang, Qianjun He*, MBene as a Theranostic Nanoplatform for Photocontrolled Intratumoral Retention and Drug Release, Advanced Materials, 2021, 33, 202008089. 4. Zhaokui Jin,# Yuan Sun,# Tian Yang, Lunbo Tan, Peixun Lv, Qingqing Xu, Geru Tao, Shucun Qin, Xifeng Lu*, Qianjun He*, Nanocapsule-mediated sustained H2 release in the gut ameliorates metabolic dysfunction-associated fatty liver disease, Biomaterials, 20 21, 276, 121030. 5. Jin Meng,# Zhaokui Jin,# Penghe Zhao, Bin Zhao, Mingjian Fan, Qianjun He*, A multistage assembly/disassembly strategy for tumor-targeted CO delivery, Science Advances, 2020, 6, eaba1362. 6. Penghe Zhao,# Zhaokui Jin,# Qian Chen, Tian Yang, Danyang Chen, Jin Meng, Xifeng Lu, Zhen Gu*, Qianjun He*, Local generation of hydrogen for enhanced photothermal therapy. Nature Communications , 2018, 9, 4241. 7 . Xiang Ling,# Zhaokui Jin,# Qi Jiang, Xiaotao Wang, Bin Wei, Zhongchang Wang, Yangsen Xu, Tianye Cao, Jonathan W. Engle, Weibo Cai, Chenliang Su*, Qianjun He*, Engineering biocompatible TeSex nano-alloys as a versatile theranostic nanoplatform, National Science Review, 2021, 8, nwaa156. 8. Zhaokui Jin,# Danyang Chen,# Penghe Zhao, Yanyuan Wen, Mingjian Fan, Gaoxin Zhou, Yingshuai Wang, Qianjun He*, Coordination-induced exfoliation to monolayer Bi-anchored MnB 2 nanosheets for multimodal imaging-guided photothermal therapy of cancer, Theran ostics, 2020, 10, 1861. 9 . Zhaokui Jin,# Penghe Zhao,# Junheng Zhang, Tian Yang, Gaoxin Zhou, Daohong Zhang, Tianfu Wang*, Qianjun He*, Intelligent metal carbonyl-MOF nanocomplex for fluorescent traceable H2O2-triggered CO delivery, Chemistry - A European Journal, 2018, 24, 11667 11674. 10. Zhaokui Jin, # Yanyuan Wen, # Yaxin Hu, Wenwen Chen, Xianfeng Zheng, Weisheng Guo, Tianfu Wang, Zhiyong Qian, Bao-Lian Su, Qianjun He*, MRI-guided and ultrasound-triggered release of NO by advanced nanomedicine, Nanoscale , 2017, 9, 3637 3645.